Description and effect of the ZERO IN ingredients

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N-ACETYL-L-TYROSINE (Tyrosine)

N-acetyl-L-tyrosine (NALT) is an acetylated form of the amino acid L-tyrosine. NALT is the starting substance for the synthesis of all catecholamines (dopamine, adrenaline, noradrenaline).

Dopamine plays an important role in brain activities related to reward, motivation, and enjoyment. It plays a key role in modulating focus, motivation, cognitive flexibility, and emotional resilience. In addition to the states related with creativity and productiveness, dopamine is one of the main regulators of motion control and coordination of body movements, so it is also important in exercise and muscle performance. Dopamine can be especially helpful as cognitive support when participating in more demanding or stressful tasks. It supports working memory, mental flexibility and information processing. In brain functions, it supports working memory, cognition, flexibility, logical reasoning, mathematical processing, convergent ("deep") thinking, and perceptual-motor tasks.

 

It protects against neurotransmitter depletion due to increased brain activity as well as against decreased performance during cognitively demanding tasks. It also protects against harmful behavioral responses and a reduction in norepinephrine levels and an increase in blood pressure caused by stress. It supports the general mood.

 

L-THEANINE (L-Theanine)

L-theanine is a calming amino acid that occurs naturally in green tea. Amino acids are an integral part of proteins that support muscle growth and regeneration. This is especially important when gaining muscle mass. L-theanine is often used with caffeine because the combination supports switching between tasks, accuracy, and mental focus. L-theanine can be broken down to glutamate, which is a building block for glutamatergic signaling (i.e., the glutamate-GABA pathway), and to glutathione, an antioxidant used for detoxification. It supports the absorption of amino acids and ensures healthy aging and longevity.

 

MUCUNA PRURIENS (Velvet Bean)

Velvet bean is a plant that grows in China and India. It has neuroprotective and adaptogenic effects. It improves mood and increases focus and motivation.

Its main active ingredient is L-DOPA. Because the latter is of natural origin, it is more effective in the body than the synthetic one. It also regulates the levels of dopamine, norepinephrine, adrenaline and serotonin in the brain.

It reduces the production of cortisol, which is released in the brain when we are under stress. It is a powerful antioxidant. It raises libido in men. It is widely used in Ayurvedic medicine, even in poisonous snake bites, also improving mood and increasing focus.

 

TURMERIC (Curcumin)

Turmeric contains an active substance called curcumin, which gives curry a yellow color. It is a very powerful antioxidant and antiseptic. As an antioxidant, it neutralizes the free radicals, while also stimulating its own antioxidant enzymes in the body. It improves brain function and reduces the risk of brain diseases. Research of the impact on Alzheimer's disease is also underway.

Curcumin stimulates the liver and gallbladder to excrete bile, bilirubin and cholesterol. It makes sure that the liver is protected from the toxins that we take into the body on a daily basis.

Because it has an antiseptic and antibacterial effect, Ayurvedic doctors use it to disinfect wounds and burns. It speeds up digestion and regulates metabolism. It is popular with anyone who wants to lose a few pounds. Due to its soothing effect, it is also very successful in treating stomach problems, as it prevents the formation of ulcers.

In recent years, Western medicine has been intensively researching all the positive effects of curcumin on the body.

 

PROANTHOCYANIDINS (Pine bark extract)

Proanthocyanidins are a group of flavonoids found in pine bark, grape seeds and other plant sources.

Their use dates back to the year 1500, when the French explorer Jacques Cartier and his sailors, during a long voyage from France to the New World, struggled with scurvy – a deficiency of vitamin C.

 

Today, we know that pine bark is a good source of vitamin C as well as many phytochemicals and natural plant compounds that support better health. The “stars” in this group are the proanthocyanidins, powerful antioxidant compounds (stronger than vitamins C and E) that provide many additional health benefits.

If you are overweight or in poor health, your body will create an excess of free radicals. These trigger inflammation in the body, damage your DNA and endanger your health. Antioxidants extinguish these internal fires. Research has shown that proanthocyanidins can prevent and reduce oxidative damage due to free radicals.

Pine bark extract has a significant effect on the level of nitric oxide (NO) in the body, which is responsible for vasodilation (dilation of blood vessels) and good blood flow. If you are struggling with low libido, erectile dysfunction or high blood pressure, raising NO levels in your body is an effective way to correct this. It reduces swelling of the legs, or significantly reduces problems with chronic venous insufficiency.

Pine bark extract can bring you some additional benefits if you are struggling with high blood sugar or diabetes.

Proanthocyanidins alleviate the cold symptoms and can shorten recovery.

They can improve your brain function.

Stress, poor diet and lack of sleep can contribute to suboptimal brain function. Pine bark extract helps here a lot. New research shows that adults over the age of 55 who have used pine bark extracts showed better results in brain-related tasks compared to groups who received placebo. Researchers believe that the benefits stem from the antioxidant effects of the extract, which are able to reduce oxidative stress (associated with poor nutrition, high stress, lack of exercise, etc.).

 

They protect the skin from sun damage.

Proper sun exposure and vitamin D are crucial for your health and vitality. Excessive and incorrect sunbathing can also have negative effects on the skin. The added pine bark extract has been proven to provide protection against harmful UVB rays and can reduce hyperpigmentation and improve skin function. If you spend a lot of time in the sun, this can be a good extra support for your skin.

They reduce inflammation.

Cytokines are a group of anti-inflammatory molecules that are released during the cold or the flu, injuries, overtraining, and even chronic health issues. Research shows that pine bark extract is able to reduce the anti-inflammatory cytokines IL-1 and IL-6, which are responsible for many of the harmful effects of chronic inflammation.

 

VITAMIN D

Vitamin D (also called "calciferol") is a fat-soluble vitamin that is naturally present in some foods, added to others (milk) and available as a dietary supplement. It can also be produced endogenously when ultraviolet (UVB) rays of sunlight hit the skin and trigger its synthesis.

Vitamin D, obtained through sun exposure, food and supplements, is biologically inert and is processed twice for its activation in the body. The first processing occurs in the liver and the second in the kidneys.

Vitamin D promotes the absorption of calcium in the intestine. It maintains adequate serum calcium and phosphate concentrations to allow for normal bone mineralization and to prevent hypocalcemic tetany (involuntary muscle contraction leading to cramps). It is also needed for bone growth and renewal. Without enough vitamin D, bones can become thin, brittle, or damaged.

The power of vitamin D also lies in the fact that it affects the immune system.

Vitamin D also has some other roles in the body, including modulation of processes such as cell growth, neuromuscular and immune function, and glucose metabolism. Many genes that regulate cell proliferation, differentiation and apoptosis partially modulate vitamin D. Many tissues have the vitamin D receptors.

Because vitamin D is fat-soluble, it has the property of storing excess in our body. The half-life of vitamin D is 15 days, which means that it can stay in the body for up to two months.

On a daily basis, the body needs 600 IU (International Units) or 15 mcg (micrograms) of vitamin D. Because the excess is stored in fat, the doses can also be higher (4000 IU). The maximum reasonable dose is 10000 IU, but at longer intervals.